The Formenti Lab


Silvia Formenti

Silvia C. Formenti, MD

Principal Investigator

Dr. Formenti received her medical degree in Italy from the University of Milan. She is board certified in medical oncology, radiology and radiation oncology. A recognized leader in radiation oncology and breast cancer research, Dr. Formenti’s groundbreaking work has transformed the paradigm in radiation biology, demonstrating the efficacy of combining radiotherapy with immunotherapy to control cancer cell growth in solid tumors. In combination with immune checkpoint blockade, focal radiotherapy can be used to recruit patients’ immune systems to reject their individual tumor, resulting in a form of personalized immunotherapy, specific for each individual patient. She has translated preclinical work into clinical trials in metastatic solid tumors like breast and lung cancer, and in brain metastases. She is currently leading six investigator-initiated clinical trials of immunotherapy and radiotherapy. A prolific researcher, Dr. Formenti has published more than 250 papers recognized by high-impact journals including Nature Medicine, JAMA, Lancet Oncology and the Journal of Clinical Oncology. In 2019, she was honored to receive the ASTRO Gold Medal.


Jeffrey Kraynak

Laboratory Supervisor

Jeffrey Kraynak was born in Cleveland, Ohio, where he graduated from John Carroll University and worked for four years at the Cleveland Clinic Foundation in Molecular Cardiology.  He spent two years in Chicago working in the Department of Rheumatology at Northwestern University and moved to New York City in June 2009, where he joined the Department of Biochemistry at NYU and later worked in a Pulmonary Function Clinic at Bellevue Hospital.  Jeffrey joined the Department of Radiation Oncology at Weill Cornell Medicine in June 2015, where he assists with numerous aspects of laboratory research and management.  Mr. Kraynak is also an accomplished author, screenwriter, and filmmaker.


Fabiana Gregucci, MD.

Dr. Gregucci earned her Doctor of Medicine and Surgery, Master's in Biostatistics, and completed her residency in Radiation Oncology from the University of Padua, Italy.  After completing her training, she joined Regional General Hospital F. Miulli - Bari (Italy), where she has been engaged in both clinical and research activities. Dr. Gregucci is an expert in breast cancer, central nervous system cancer, and stereotactic radiotherapy. She was an executive board member of the Italian Association of Radiotherapy and Clinical Oncology (AIRO) study group for Breast Cancer and Central Nervous System. In 2017, she was awarded an AIRO Scholarship for an international training project and completed the training program on Radiomics Research at MD Anderson Cancer Center (Texas, USA). During the last years, she developed deeply interest and skills in clinical research following several projects and finalizing data publication. Since 2022, under Dr. Formenti’s mentorship, Dr. Gregucci is fellow in Radiation Oncology, improving her knowledge and skills in clinical and translational research, mostly focused on the field of radiotherapy, immunotherapy, and immune system response again cancer.

Schedule Appointment

There are many ways to request for an appointment with us. Give us a call at the information below, login to your Weill Cornell Connect or fill out the online form.

Contact Us

David H. Koch Center

New York-Presbyterian Hospital/
Weill Cornell Medical Center
1283 York Avenue, 4th floor
New York, NY 10065
Tel: (212) 746-3600
View Map

Stich Radiation Oncology Center

New York-Presbyterian Hospital/
Weill Cornell Medical Center
525 East 68th Street
New York, NY 10065
Tel: (212) 746-3600
View Map

The Arnold Center For Radiation Oncology

New York-Presbyterian Hospital Queens
56-45 Main Street
(56th Avenue between Main Street and 141st Street)
Flushing, NY 11355
Tel: (718) 670-1501

View Map