Summary
The Radiation Therapy Preclinical Core (RTPC) of Weill Cornell Medicine offers advanced, clinically relevant treatments for in vitro and in vivo research using the Xstrahl Small Animal Radiation Research Platform (SARRP).
The SARRP is a sophisticated pre-clinical radiation therapy (RT) system that combines high-resolution micro-CT imaging with precise beam delivery capabilities. Its integrated imaging allows for detailed anatomical visualization, enabling accurate tumor localization, while advanced collimators and beam filtration ensure highly targeted radiation with customizable beam properties. Motorized stages and software-driven treatment planning further enhance precision and reproducibility, making the SARRP an ideal platform for conducting clinically relevant small animal studies.
Overview
History: Established in 2020 through NIH grant S10 RR027619-01 (P.I. Formenti SC), the Core also provides expert consultation on experimental design, data analysis, anesthesia, and cone beam CT imaging services.
Location and access: Located in Room E213 on the second floor of the E Building at 1300 York Avenue, New York, NY, the Core is accessible to researchers from Weill Cornell Medicine, Cornell University, Rockefeller University, Memorial Sloan Kettering Cancer Center, Hospital for Special Surgery, and other Cornell-affiliated institutions. Services are also available to external academic and commercial investigators.
Consultation: Expert guidance on experimental design, dose planning, image registration, and sample handling.
Small Animal Irradiation: Targeted treatments with options for single, multi-beam, or arc therapy, using image guidance (i.e. cone-beam CT and MRI) for advanced tumor visualization and treatment planning.
Anesthesia: Isoflurane induction chamber available for small animal procedures.
Cell Irradiation: Open-field irradiation for various culture formats, including 10 cm dishes, multi-well plates, and T-75 flasks
Fees:
Assisted irradiation (Academia)
$150/hour
Assisted irradiation (Non-academia)
$300/hour
Operator Assisted Treatment
Services are provided by trained staff Monday through Friday, 9:00AM to 5:00PM
Contact
Jeffrey Kraynak
Manager, WCM Radiation Therapy Preclincal Core
(646) 962-2260
Claire Vanpouille-Box, PhD
Director, Radiation Therapy Preclincal Core
(646) 962-2125