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Radiation Oncology

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Radiation Therapy Preclinical Core

SARRP

Summary

The WCM Radiation Biology Core Facility offers state-of-the-art targeted radiation treatments for cells and small animals with accuracy equivalent to clinical radiotherapy. The XStrahl SARRP small animal irradiator was obtained with a NIH small instrumentation grant, NIH S10 RR027619-01 (P.I. Formenti SC). The core also provides expert consultation on project design, data analysis, anesthesia, and cone beam CT imaging services.

Overview

History: The Radiation Biology Core Facility is established in 2020 by the Department of Radiation Oncology.

Location: The core is located on the second floor of the “E” building in Room E213. 1300 York Avenue, New York, NY.

Open to all: The resources and services of the core facility are open to all investigators at Weill Cornell Medicine, Cornell University, Rockefeller University, Memorial Sloan Kettering Cancer Center, Hospital for Special Surgery, and all Cornell-affiliated institutions. The facility also provides services to external investigators at both academic institutions and commercial enterprises.

Resources

Small Animal Radiation Research Platform (SARRP), assisted use only

Muriplan treatment planning software located on a workstation in the core facility and is available on an hourly basis with assistance and consultation from core staff.

Services

Open field Irradiation of Cells:

cells

  • 10cm dish, multi-well plate, or T-75 flask
  • (4) 60mm plates

Irradiation of subcutaneous tumors in mice:

mouse tumor

  • Up to (2) mice simultaneously with 10x10mm collimator

Consultation: Core staff is available to consult on all animal irradiations; experimental design, dose recommendation, sample preparation, etc.

Imaging: MRI image registration with Cone-beam CT imaging (CBCT) in mice.

Targeted treatment of internal tumor with CBCT scanning

  • Single, multi-beam, or arc treatment
  • Targeting down to 0.5mm

Anesthesia: Isoflurane induction chamber for small animals.

Operator Assisted Treatment

Treatment service is provided by a trained scientist to users on an hourly basis on our SARRP. Available Monday – Friday 9 am to 5 pm.

Contact

Jeffrey Kraynak

Manager, WCM Radiation Biology Core Facility

sarrupusers@med.cornell.edu

(212) 962-2260

 

Ariel Marciscano, MD

Director, Radiation Biology Core Facility

arm7007@med.cornell.edu

(212) 746-9821

 

 

Schedule Appointment

There are many ways to request for an appointment with us. Give us a call at the information below, login to your Weill Cornell Connect or fill out the online form.

Contact Us

David H. Koch Center

New York-Presbyterian Hospital/
Weill Cornell Medical Center
1283 York Avenue, 4th floor
New York, NY 10065
Tel: (212) 746-3600
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Stich Radiation Oncology Center

New York-Presbyterian Hospital/
Weill Cornell Medical Center
525 East 68th Street
New York, NY 10065
Tel: (212) 746-3600
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The Arnold Center For Radiation Oncology

New York Hospital Queens
56-45 Main Street
(56th Avenue between Main Street and 141st Street)
Flushing, NY 11355
Tel: (718) 670-1501

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New York-Presbyterian/
Lower Manhattan Cancer Center

21 West Broadway
New York, NY 10003
Tel: (212) 746-6600

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